Metabolic consequences of modern immunosuppressive agents in solid organ transplantation
نویسندگان
چکیده
منابع مشابه
State of immunosuppressive agents in organ transplantation.
TRANSPLANT A nON has been built on the foundation of using drug thera.py to nonspecifically suppress the recipient immune response. Failure to achieve adequate immunosuppression is associated with a high incidence of graft loss from rejection. The present goal of immunosuppressive regimens is to suppress the immune response to the allograft while preserving sufficient immunity to avoid opportun...
متن کاملImmunosuppressive drugs after solid organ transplantation.
In recent years solid organ transplantation has been rapidly developed as a therapeutic intervention that is life-saving and greatly contributes to a better quality of life in organ recipients. The rapid development has been made possible because of a drastic expansion in the immunosuppressive repertoire. Unfortunately, the side effects of these drugs can be severe, which is one of the reasons ...
متن کاملImmunosuppressive Strategies in Solid Organ Transplantation 141 IMMUNOSUPPRESSIVE STRATEGIES IN SOLID ORGAN TRANSPLANTATION Pharmacotherapy Self-Assessment Program, 5th Edition
1. Justify the rationale for using multiple drug regimens in recipients of solid organ transplants. 2. Analyze the limitations of established immunosuppressive strategies. 3. Evaluate the relative benefits and risks of withdrawal and avoidance immunosuppressive strategies. 4. Design and implement immunosuppressive strategies aimed at decreasing toxicity and improving long-term patient outcomes....
متن کاملMetabolic syndrome and solid-organ transplantation.
The metabolic syndrome is proposed as a cluster of known cardiovascular risk factors, interrelated by a common pathophysiological defect, that symbolize a heightened metabolic burden. Advocates of the concept argue that it is a predictor for both diabetes and cardiovascular disease, complications of great importance posttransplantation. The abundant medical literature on the topic is now expand...
متن کاملNeurotoxicity of immunosuppressive therapies in organ transplantation.
ABSTRACT Immunosuppressive agents have revolutionized clinical transplantation medicine, allowing the avoidance of immune system attack on the transplanted graft. Nevertheless, the use of medications such as cyclosporine, tacrolimus and others also brought the side effects of these drugs. Early identification of drug-induced neurotoxicity in transplanted patients and of its specific causes is i...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Therapeutic Advances in Endocrinology and Metabolism
سال: 2016
ISSN: 2042-0188,2042-0196
DOI: 10.1177/2042018816641580